Gay and bisexual men in the United States should now be allowed to donate blood, according to authorities.
They have been banned from doing so since the AIDS epidemic in the 1980s.
The US Food an Drug Administration is recommending the lifting of the restriction, BBC News reported Wednesday.
However, men who have had sex with other men in the previous 12 months will still be banned, the FDA said in a statement.
The move brings the US into line with other countries such as Britain, Australia and Spain, which have lifted outright bans in recent years.
New guidelines will be drafted in early 2015 and then a consultation period will follow.
At present, the ban excludes men who have had sex with other men at any time since 1977.
Campaigners have long argued the ban discriminates against gay and bisexual men and reinforces negative stereotypes.
And due to advances in HIV testing, the American Medical Association and other groups say the lifetime ban is no longer supported by science.
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